An Allograft is a tissue that is removed from a human donor which means the donor material comes from a member of the same species, but the donor is not genetically identical to the recipient. Over 1,000,000 al¬lografts are implanted each year. The use of musculoskeletal allograft tissue in reconstructive orthopedic surgeries has markedly increased over the last decade. Because of inadequate amounts of autograft and the limited size and shape of a person’s own bone, allograft is commonly used in reconstructive surgery of the hip, knee and long bones, as well as in cases of bone loss due to trauma or tumors. Using allograft tissue from another person can eliminate the need for a second operative site to remove autograft bone or tendon, reduce the risk of infection at a separate surgical site, and safeguard against pain and loss of function at or near the secondary site. Because of tissue processing, cells responsible for tissue rejection are removed or inactivated so after surgery, there is no need for immunosuppressive therapy.